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recombinant human adam 10  (R&D Systems)


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    Structured Review

    R&D Systems recombinant human adam 10
    Recombinant Human Adam 10, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 50 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+adam+10/Recombinant+Human+ADAM10+Protein%2C+CF/us12612459-769-0-14
    Average 93 stars, based on 50 article reviews
    recombinant human adam 10 - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Recombinant:

    Article Title: Multiple metalloproteinases process protransforming growth factor-alpha (proTGF-alpha).
    Article Snippet: Shedding of TNF-R requires a single cleavage event, whereas the ectodomain of proTGF-R is cleaved at N-proximal (N-terminal) and membrane proximal (C-terminal) sites to release mature TGFR.. Tumor necrosis factor-R converting enzyme (TACE) was shown to have a central role in the shedding of both factors.. Here we show that cleavage of the proTGF-R C-terminal site, required for release of mature growth factor, is less sensitive to a panel of hydroxamates than TNF-R processing.

    Article Title: Differential regulation of soluble and membrane CD40L proteins in T cells.
    Article Snippet: CD40 ligand is an important immunoregulatory protein expressed by T cells.. This protein exists as two isoforms, a membrane glycoprotein and a truncated soluble form.. Here we demonstrate that membrane and soluble CD40L (sCD40L) are diVerentially regulated depending upon the activation stimulus.

    Article Title: Methods of identifying agents that block MCD28 cleavage by MMPS
    Article Snippet: Matrix Metalloproteinases and ADAM's—Commercial recombinant human metalloproteinases MMP-1 (Cat. No. AS-55575), MMP-9 (Cat. No. AS-55576), MMP-10 (Cat. No. AS-72067), MMP-12 (Cat. No. AS-55525) and MMP-13 (Cat. No. AS-72257) are from AnaSpec. .. Recombinant human ADAM-10 (Cat. No. 936-AD) and ADAM-17 (Cat. No. 930-ADB) were purchased from R&D system. .. Recombinant human MMP-2 was used both from Anaspec (Cat. No. AS-72005) and R&D system (Cat. No. 902-MP).

    Article Title: Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes.
    Article Snippet: .. 5 nM recombinant human ADAM-10 (R&D Systems, Minneapolis, USA) was mixed with an appropriate amount of TIMP-1 in 20 mM Tris/HCl, pH = 8.0, 0.006 % Tween-20, in a volume of 50 μl. .. 10 μM fluorogenic substrate peptide (Mca-K-P-L-GL-Dpa-A-R-NH2, R&D Systems, Minneapolis, USA) was added in a volume of 50 μl.

    Incubation:

    Article Title: Differential regulation of soluble and membrane CD40L proteins in T cells.
    Article Snippet: CD40 ligand is an important immunoregulatory protein expressed by T cells.. This protein exists as two isoforms, a membrane glycoprotein and a truncated soluble form.. Here we demonstrate that membrane and soluble CD40L (sCD40L) are diVerentially regulated depending upon the activation stimulus.



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